Oxyphenisatin acetate, the pro-agent of oxyphenisatin, is used to be a laxative. In Vitro Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468. In the estrogen receptor (ER) positive MCF7 and T47D cells, oxyphenisatin acetate induces TNFα expression and TNFR1 degradation, indicating autocrine receptor-mediated apoptosis in these lines. Ten micromoles per liter Oxyphenisatin acetate treatment results in autophagy and mitochondrial dysfunction. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Oxyphenisatin acetate (300 mg/kg, i.p.) delivers intraperitoneally inhibited tumor growth, accompanied by phosphorylation of eIF2α and degradation of TNFR1 in an MCF7 xenograft model . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Oxyphenisatin acetate
CAS number：115-33-3 molecular formula：C24H19NO5
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| Chinese alias | 醋酸奥芬那敏 | 双醋酚丁标准品 | 双醋酚丁衍生物 | 双丙酚丁 | 双丙富马酸盐 | ||
| English alias | 3,3-Bis(p-acetoxyphenyl)oxindole | CHEBI:135638 | Oxyphenisatine di(acetate) | Diphesatine | OXYPHENISATIN ACETATE [MI] | Oxyphenisatin acetate (USAN) | SB64142 | D05320 | NSC117186 | STL257074 | (2-Oxoindoline-3,3-diyl)bis(4,1-phenylene) diacetate | ||
| CAS number | 115-33-3 | molecular formula | C24H19NO5 |
| molecular weight | 401.41 g/mol | Exact mass | - |
| PSA | 81.700 Ų | logp | 3.5 |
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