内消旋-2,3-二巯基琥珀酸（DMSA）用于在Mg/Ti/Au微电机上形成单层膜，以增强其从污染的水溶液中对有毒重金属污染物（Zn（II）、Cd（II）和Pb（II））的螯合能力。它可用于：作为还原和稳定剂，合成单层保护的金簇；用于油胺涂覆的F3O4纳米粒子的末端羧化，以开发靶向姜黄素的药物递送系统。 DMSA (Meso-2,3-dimercaptosuccinic acid) is a potent lead chelating agent found to be a scavenger of reactive oxygen species (ROS). Murine experiments have shown that this compound also lowers blood pressure in rat arterial hypertension via a decrease in total cell calcium levels. It has also been observed that DMSA upregulates mRNA expression of macrophage-1 antigen, L-, E-, and P-selectin, as well as causing an increase in TNFα (tumor necrosis factor-α) concentrations in murine lung. Mechanistic studies suggest that DMSA is metabolized into mixed disulfides of cysteine, which are active chelating agents. A water-soluble chelating agent.
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meso-2,3-Dimercaptosuccinic acid (DMSA)
Dangerous GoodsCAS number：304-55-2 molecular formula：C4H6O4S2
overview
compound introduction
Specs
| Chinese alias | 二巯基丁二酸 | 2,3-二硫代-内消旋酒石酸 | ||
| English alias | DIM-SA | DMS | DMSA | DMSA (Meso-2,3-dimercaptosuccinic acid) | HSDB 6783 | meso-Dimercaptosuccinic acid | Acid, meso-Dimercaptosuccinic | Butanedioic acid, 2,3-dimercapto-, (R*,S*)- | Succimero [INN-Spanish] | SUCCIMER [USAN] | D00572 | meso-2,3-Dimercap | ||
| CAS number | 304-55-2 | molecular formula | C4H6O4S2 |
| molecular weight | 182.22 g/mol | Exact mass | ≥98% |
| PSA | 76.600 Ų | logp | 0.1 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08 , GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
2
Personal protective equipment：
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS：
WM7650000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
304-55-2 | meso-2,3-Dimercaptosuccinic acid.pdf
