RG-13022是酪氨酸激酶酪氨酸磷酸化抑制剂。报告表明,在癌细胞研究中,RG-13022抑制表皮生长因子(EGF)刺激的癌细胞增殖。此外,已描述了RG-13022可以抑制EGF,血小板衍生的生长(PDGF)信号传导和PDGF增强的DNA合成。RG-13022是EGFR和PDGFR的抑制剂。 RG-13022 is a Tyrosine kinase tyrphostin. Reports indicate that RG-13022 suppresses epidermal growth factor (EGF)-stimulated cancer cell proliferation in cancer cell studies. Additionally, RG-13022 has been described to inhibit EGF, platelet-dervied growth (PDGF) signaling, and PDGF enhanced DNA synthesis. RG-13022 is an inhibitor of EGFR and PDGFR.
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RG-13022
Dangerous GoodsCAS number:136831-48-6 molecular formula:C16H14N2O2
overview
compound introduction
Specs
| Chinese alias | 酪氨酸磷酸化抑制剂RG 13022 | 3-(3,4-二甲氧基苯基)-2-(吡啶-3-基)丙烯腈 | ||
| English alias | 3-(3,4-Dimethoxyphenyl)-2-(pyridin-3-yl)acrylonitrile | ||
| CAS number | 136831-48-6 | molecular formula | C16H14N2O2 |
| molecular weight | 266.3 g/mol | Exact mass | ≥98% |
| PSA | 55.100 Ų | logp | 2.600 |
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WGK Germany:
3
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