compound introduction
Tyrphostin RG 14620是非酚型tyrphostin类似物，对EGFR（EGF受体）具有选择性。该化合物抑制EGF刺激的HER14细胞增殖（IC | 50 | = 3μM）以及体内肿瘤的生长。Tyrphostin RG 14620对肾和膀胱癌细胞系具有抗增殖作用。Tyrphostin RG 14620是酪氨酸激酶的抑制剂。 Tyrphostin RG 14620 is a non-phenolic tyrphostin analog, which is selective for the EGFR (EGF receptor). The compound inhibits EGF-stimulated HER14 cell proliferation (IC|50|=3 μM) as well as tumor growth in vivo. Tyrphostin RG 14620 contains anti-proliferative effects on renal and bladder carcinoma cell lines. Tyrphostin RG 14620 is an inhibitor of Tyrosine Kinase.
