compound introduction
Ridaforolimus (Deforolimus, MK-8669)是一种选择性的mTOR抑制剂，IC50为0.2 nM；对mTOR信号通路的抑制作用及与FKBP12结合能力和Rapamycin接近。 A selective FRAP (mTOR) inhibitor
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Ridaforolimus (Deforolimus, MK-8669)
Dangerous GoodsCAS number：572924-54-0 molecular formula：C53H84NO14P
overview
Specs
| Chinese alias | 药雷帕霉素 | ||
| English alias | AP23573 | Deforolimus (MK-8669) | AKOS030526165 | NSC757440 | NSC-757440 | CCG-270602 | Q2151796 | Deforolimus | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-12-((1R)-2- ((1S,3R,4R)-4-((Dimethylphosphinoyl)oxy)-3-methoxycyclohexyl)-1-methyl | ||
| CAS number | 572924-54-0 | molecular formula | C53H84NO14P |
| molecular weight | 990.21 g/mol | Exact mass | - |
| PSA | 202.000 Ų | logp | 5.9 |
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physicochemical properties
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Safety information
pictogram：
GHS08 , GHS09
Signal word：
Warning
Hazard Statement：
H373: 通过长时间或反复暴露对器官造成损害 H400: 对水生生物有剧毒 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P391: 收集溢出物 P203: 使用前，获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心，请就医。 P319: 如果你感到不适，请寻求医疗帮助。
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MSDS
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