盐酸地布卡因是喹诺酮类衍生物,以靛红为起始物料,经一系列反应可制得盐酸地布卡因。它是一种局部麻醉剂。 Information Dibucaine HCl Dibucaine HCl (Cinchocaine) is a local anesthetics. Targets Sodium channel In vitro Dibucaine (Cinchocaine) HCl is one of the most potent and toxic of the long-acting local anesthetics. Dibucaine (Cinchocaine) HCl blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane\'s permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
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Dibucaine HCl
Dangerous GoodsCAS number:61-12-1 molecular formula:C20H29N3O2.HCl
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Cincaine chloride | Cinchokain hydrochlorid | AS-33525 | Cinchocaine hydrochloride, European Pharmacopoeia (EP) Reference Standard | Percain | DIBUCAINE HYDROCHLORIDE [MI] | MFCD00012735 | Nupercaine hydrochloride (TN) | Benzolin (local anesthetic) | CINC | ||
| CAS number | 61-12-1 | molecular formula | C20H29N3O2.HCl |
| molecular weight | 379.92 g/mol | Exact mass | - |
| PSA | 54.500 Ų | logp | 4.294 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS09 , GHS05 , GHS07
Signal word:
Danger
Hazard Statement:
H411: 对水生生物有毒并具有长期持续影响 H302: 吞食有害 H318: 造成严重的眼睛损伤 H317: 可能引起皮肤过敏反应
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P272: 被污染的工作服不允许离开工作场所 P333+P313: 如发生皮肤刺激或皮疹:求医/就诊。 P362+P364: 脱掉沾污的衣服,
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
61-12-1 | Dibucaine Hydrochloride, United StatesPharmacopeia (USP) Reference Standard.pdf





