CAS number：3877-86-9 molecular formula：C30H44O7
Cucurbitacin D is an active component in Trichosanthes kirilowii , disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf , Cdk6 , pAkt) maturation without induction of the heat shock response. Anti-cancer activity Form:Solid IC50& Target:HSP90
| Chinese alias | 葫芦素D | ||
| English alias | (23E)-2beta,16alpha,20,25-tetrahydroxy-10alpha-cucurbita-5,23-diene-3,11,22-trione | NSC 308606 | 19-Nor-9-beta,10-alpha-lanosta-5,23-diene-3,11,22-trione, 9-methyl-2-beta,16-alpha,20,25-tetrahydroxy- | 19-Norlanosta-5,23-diene-3,11,22-trione,2,16,20,25-t | ||
| CAS number | 3877-86-9 | molecular formula | C30H44O7 |
| molecular weight | 516.67 g/mol | Exact mass | ≥99% |
| PSA | 132.000 Ų | logp | 2.100 |
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