Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans , improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway In Vitro Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: 3T3-L1 cell. Concentration: 1-500 μM. Incubation Time: 48 h. Result: Did not cause significant cell death up to 500 μM concentration. Cell Viability AssayCell Line: 3T3-L1 cell. Concentration: 5 μM, 10 μM, 15 μM. Incubation Time: 8 days (replaced every 2 days). Result: LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation. Form:Solid IC50& Target:PPARγ GLUT4
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Licarin B
CAS number：51020-87-2 molecular formula：C20H20O4
overview
compound introduction
Specs
| Chinese alias | 利卡林B | ||
| English alias | BDBM50303148 | Q-100947 | 5-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole | AKOS030632872 | NSC 370990 | HY-N0479 | licarine B | SCHEMBL12604783 | (+)-licarin B | DTXSID601317642 | AC-34420 | licarinB | | ||
| CAS number | 51020-87-2 | molecular formula | C20H20O4 |
| molecular weight | 324.4 g/mol | Exact mass | ≥99% |
| PSA | 36.900 Ų | logp | 4.600 |
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