Application: Thalidomide has been used to study its teratogenic effects in chicken embryos and human embryonic cells. This study reported that thalidomide causes limb defects by stabilizing PTEN, inhibiting the expression of Akt and activating caspase-dependent apoptosis. Thalidomide has also been used for studying glutathione mediated teratogenic resistance in mouse embryos.
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(R)-(+)-Thalidomide
Dangerous GoodsCAS number:2614-06-4 molecular formula:C13H10N2O4
overview
compound introduction
Specs
| Chinese alias | R-(+)-2-(2,6-二氧代-3-哌啶基)-1H-异吲哚-1,3(2H)-二酮 | ||
| English alias | (+)-Thalidomide | CCG-36381 | EN300-7507077 | 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione | CHEBI:61917 | R-(D)-THALIDOMIDE | 2-[(3R)-2,6-dioxopiperidin-3-yl]-1H-isoindole-1,3(2H)-dione | 6EL | R-(+)-Thalidomide | D-Thalidomide | D | ||
| CAS number | 2614-06-4 | molecular formula | C13H10N2O4 |
| molecular weight | 258.23 g/mol | Exact mass | - |
| PSA | 83.600 Ų | logp | 0.300 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H302: 吞食有害 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P203: 使用前,获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽:请寻求医疗帮助。 P318: 如果暴露或担心,请就医。
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downstream information
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MSDS
Found 0 shareMSDS





