应用 乙醇醛二聚体可用于 3,4-二氮杂-2-己烯-1,6-二醇的合成,后者可经过氢化反应形成 1,2-双(2-羟乙基)肼。它在手性催化剂存在下与 2,3-二氢呋喃发生环加成反应,形成稠合的双环四氢呋喃 (bis-THF) 醇——一种 HIV 蛋白酶抑制剂的关键基团。 Description Glycolaldehyde dimer may be used in the synthesis of 3,4-diaza-2-hexene-1,6-diol, which can undergo hydrogenation to form 1,2-bis(2-hydroxyethyl)hydrazine. It undergoes cycloaddition with 2,3-dihydrofuran in the presence of a chiral catalyst to form fused bicyclic tetrahydrofuran (bis-THF) alcohol, a key moiety of HIV protease inhibitors.
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Glycolaldehyde dimer
Dangerous GoodsCAS number:23147-58-2 molecular formula:C4H8O4
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | [1,4]-dioxan-2,5-diol | EINECS 204-590-2 | DTXSID60945822 | JNG39F464R | Glycoaldehyde dimer | 1,4-Dioxane-2,5-diol # | 14-Dioxane-25-diol | D92592 | SCHEMBL52731 | 2,5-DIHYDROXY-P-DIOXANE | FT-0602682 | s3334 | 1,4-Dioxane-2,5-diol | AM20090246 | EN300-8 | ||
| CAS number | 23147-58-2 | molecular formula | C4H8O4 |
| molecular weight | 120.1 g/mol | Exact mass | 结晶的,立体异构体的混合物。根据立体异构 |
| PSA | 58.900 Ų | logp | -1.300 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水
WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
23147-58-2 | Glycolaldehyde dimer.pdf





