1-deoxysphinganine is synthesized by the condensation of palmitic acid with alanine or glycine in the presence of enzyme serine palmitoyltransferase (SPT). It is metabolized to 1-deoxyceramides. Application 1-deoxysphinganine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing in MN9D dopaminergic neuroblastoma cell line. It is also suitable for use as a neurotoxic agent in human CD8+ T cells.
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1-deoxysphinganine (m18:0)
CAS number:196497-48-0 molecular formula:C18H39NO
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 1-deoxysphinganine | 1-deoxy-sphinganine | DoxSA cpd | AS-65840 | Tartrazine B | (2S,3R)-2-amino-3-hydroxyoctadecane | 1-deoxysphinganine, 1-deoxysphinganine (m18:0), powder | BDBM50496601 | Spisulosine | UNII-ZX5D253CYY | i17:0 | (2S, 3R)-2-amino-3-octad | ||
| CAS number | 196497-48-0 | molecular formula | C18H39NO |
| molecular weight | 285.508 g/mol | Exact mass | ≥99% |
| PSA | 46.300 Ų | logp | 6.900 |
numbering system
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physicochemical properties
No physical and chemical property information yet
Safety information
WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
1-Deoxysphinganine | 1-deoxysphinganine (m18:0)





