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1-Methyl-3-indoleacetic acid

Dangerous Goods

CAS number:1912-48-7    molecular formula:C11H11NO2

overview

compound introduction

·Reactant for enantioselective preparation of α-aryl alkylcarboxylic acids·Reactant for preparation of PKC inhibitor methylindolylpyridinylmet hylpiperidinylindolylpyrr oledione for protein kinase C imaging·Reactant for stereoselective preparation of δ-lactones via Michael addition/lactonization with unsaturated carboxylates·Reactant for stereoselective preparation of vindorosine, vindoline, and analogs·Reactant for preparation of (indolyl)pyrrol-2-ones as VEGF-R inhibitors, antiangiogenic agents, and protein kinase inhibitors·Reactant for synthesis of 3-aryl-5-alkyl-2,5-dihydr ofuran-2-ones and their carbanalogues as antifungal agents. 1-Methyl-3-indoleacetic acid is an indole derivative. Direct and riboflavin- or Rose-Bengal-sensitized photo-oxidation of 1-methyl-3-indoleacetic acid in aqueous buffer (pH 5 or pH 8) containing 10% methanol has been studied. ·Reactant for enantioselective preparation of α-aryl alkylcarboxylic acids·Reactant for preparation of PKC inhibitor methylindolylpyridinylmet hylpiperidinylindolylpyrr oledione for protein kinase C imaging·Reactant for stereoselective preparation of δ-lactones via Michael addition/lactonization with unsaturated carboxylates·Reactant for stereoselective preparation of vindorosine, vindoline, and analogs·Reactant for preparation of (indolyl)pyrrol-2-ones as VEGF-R inhibitors, antiangiogenic agents, and protein kinase inhibitors·Reactant for synthesis of 3-aryl-5-alkyl-2,5-dihydr ofuran-2-ones and their carbanalogues as antifungal agents.

Specs

Chinese alias-
English aliasEX-A4158 | Oprea1_357939 | 1-methyl-3-indolylacetic acid | (1-methyl-3-indolyl)acetic acid | (1-methyl-3-indolyl)-acetic acid | 1-methyl-3-indole acetic acid | 1-Methyl-3-indoleacetic acid | N-methyl-3-indoleacetic acid | NSC 78007 | 7L-904 | (1-methyl-1{
CAS number1912-48-7molecular formulaC11H11NO2
molecular weight189.21 g/molExact mass≥98%
PSA42.200 Ųlogp1.500

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS05 , GHS07
Signal word:
Danger
Hazard Statement:
H315: 引起皮肤刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害 H318: 造成严重的眼睛损伤
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P403+P233: 存放在通风良
WGK Germany:
3

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

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