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2-Aminopurine

Dangerous Goods

CAS number:452-06-2    molecular formula:C5H5N5

overview

compound introduction

含1分子结晶水的为针状结晶,水中溶解度18℃撕为0.8%,100℃时为33%。溶于酸,微溶于热乙醇,不溶于碱溶液。生物学和医学上用做6-氨基嘌呤的对抗剂。 2-氨基嘌呤(2-AP)用于特异性地抑制双链RNA依赖的蛋白激酶,蛋白激酶R(PKR)。 产品应用: 2-氨基嘌呤(2-AP)可用于双链RNA依赖性蛋白激酶、蛋白激酶R(PKR)的特异性抑制。 αα2-氨基嘌呤已被用于抑制骨关节炎(OA)软骨细胞的真核起始因子2(eIF2)-磷酸化。 2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR). Product Application: 2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes. 2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR).

Specs

Chinese alias2-氨基嘌呤 | 异腺嘌呤
English alias2-AP | AKOS006220998 | 2'-amino-purine | 2-aminopurine | NSC24129 | NSC-24129 | PD044966 | 2-amino purine | HY-W012642 | NSC 24129 | AC-13347 | 2BP | DTXSID40196416 | SQ 22,451 | SQ 22451 | 1H-PURIN-2-AMINE | MLS001333096 | 7H-Purin-2-ylamine | 9H-Purin-2
CAS number452-06-2molecular formulaC5H5N5
molecular weight135.13 g/molExact mass≥98%
PSA80.500 Ųlogp-0.200

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
WGK Germany:
3
RTECS:
UO7475000

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 1 shareMSDS
452-06-2 | Famciclovir Related Compound E, UnitedStates Pharmacopeia (USP) ReferenceStandard.pdf