Delphinidin chloride 是一种花青素,是一种可从浆果和红酒中分离得到的天然植物色素,是某些花青素的前体。Delphinidin chloride 诱导血管内皮释放一氧化氮,引起血管松弛。在1 ~ 40 μM 剂量下,对上皮生长因子受体的信号传导和雌激素受体α的表达有抑制作用,与细胞凋亡和自噬有关。Delphinidin chloride 能调节 JAK/STAT3 和 MAPKinase 信号传导。Delphinidin 还能抑制 p300/CBP 的组蛋白乙酰转移酶活性(IC50 在约为30 μM)。 Delphinidin chloride is a type of anthocyanin, a natural plant pigment that can be isolated from berries and red wine, and it is a precursor of certain anthocyanins. Delphinidin chloride induces the release of nitric oxide from the vascular endothelium, causing vascular relaxation. At doses ranging from 1 to 40 μM, it has an inhibitory effect on the signal transduction of epithelial growth factor receptors and the expression of estrogen receptor α, which is related to apoptosis and autophagy. Delphinidin chloride can regulate JAK/STAT3 and MAPKinase signal transduction. Delphinidin can also inhibit the histone acetyltransferase activity of p300/CBP (IC50 at approximately 30 μM).
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Delphinidin chloride
Dangerous GoodsCAS number:528-53-0 molecular formula:C15H11ClO7
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chromenylium chloride | ||
| CAS number | 528-53-0 | molecular formula | C15H11ClO7 |
| molecular weight | 338.70 g/mol | Exact mass | - |
| PSA | 122.000 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS08
Signal word:
危险
Hazard Statement:
H413: 可能对水生生物造成长期的有害影响 H304: 吞咽并进入呼吸道可能致命
Statement of Preventive Measures:
P273: 避免释放到环境中。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P331: 不要催吐 P301+P316: 如果吞咽:立即寻求紧急医疗救助。
Production methods and uses
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upstream information
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downstream information
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MSDS
Found 1 shareMSDS
528-53-0 | Delphinidin chloride.pdf





