Benzolamide (CL11366) 是一种有效的碳酸酐酶 (CA) 抑制剂,抑制hCA I,hCA II,EcoCAγ 和 VchCAγ 的 Ki 值分别为15 nM,9 nM,94 nM 和 78 nM。Benzolamide 还抑制 CAS3,Ki 值为 54 nM。Benzolamide 可用于青光眼和癫痫的研究。 Benzolamide (CL11366) is a potent carbonic anhydrase (CA) inhibitor, with Kis of 15 nM, 9 nM, 94 nM and 78 nM for hCA I, hCA II, EcoCAγ and VchCAγ, respectively. Benzolamide also inhibits CAS3, with a Ki of 54 nM. Benzolamide can be used for the research of glaucoma and seizures
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Benzolamide
CAS number:3368-13-6 molecular formula:C8H8N4O4S3
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| Chinese alias | - | ||
| English alias | 5-(benzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide | BDBM10886 | 2-N-benzene-1,3,4-thiadiazole-2,5-disulfonamide | AS-78505 | HY-118467 | 1,3,4-Thiadiazole-2-sulfonamide, 5-benzenesulfonamido- | 2-benzenesulfonamido-1,3,4-thiadiazole-5-sulfonamide | D | ||
| CAS number | 3368-13-6 | molecular formula | C8H8N4O4S3 |
| molecular weight | 320.37 g/mol | Exact mass | - |
| PSA | 177.000 Ų | logp | 0.1 |
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