Arbutamine is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine stimulates cardiac β 1 -, tracheal β 2 -, and adiopocyte β 3 - adrenergic receptors. Arbutamine provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine can be used for cardiac stress agent In Vitro Arbutamine (0.1-100 nM) increases heart contractile force and pD 2 value of 8.45. Arbutamine has the affinity constants (KA) value of 7.32 for cardiac β 1 -adrenergic receptors. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Arbutamine (i.v.; 5, 10, 50, 100, and 250 ng/kg/min) increases mean heart rate, peak positive left ventricular pressure and its first time-derivative, and normal-zone myocardial thickening in 8 open-chest dogs (mean weight, 26.91 kg). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:β-adrenoceptor
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
Arbutamine
CAS number：128470-16-6 molecular formula：C18H23NO4
overview
compound introduction
Specs
| Chinese alias | 阿布他明 | ||
| English alias | B07L15YAEV | ARBUTAMINE | Arbutaminum | 1,2-BENZENEDIOL, 4-(1-HYDROXY-2-((4-(4-HYDROXYPHENYL)BUTYL)AMINO)ETHYL)-, (1R) | 4-[(1R)-1-hydroxy-2-{[4-(4-hydroxyphenyl)butyl]amino}ethyl]benzene-1,2-diol | CHEBI:50580 | DB01102 | ARBUTAMINE [INN] | Arbutaminum [ | ||
| CAS number | 128470-16-6 | molecular formula | C18H23NO4 |
| molecular weight | 317.38 g/mol | Exact mass | ≥98% |
| PSA | 93.000 Ų | logp | 0.900 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
