Dimethyloxallyl Glycine(DMOG)是可渗透入细胞的HIF-1α脯氨酰羟化酶(HIF-PH)竞争性抑制剂。 用途 二甲基草酰甘氨酸(DMOG)用作TET3蛋白抑制剂。 DMOG用于: 缺氧诱导因子(HIF)活性测定 研究其对HIF-1α降解和肾脏再生的影响 脂肪组织DMOG预处理 CD34+细胞原代液体培养的媒介对照 刺激内皮细胞 Dimethyloxallyl Glycine(DMOG) is a cell permeable, competitive inhibitor of HIF-PH(HIF-1α prolyl hydroxylase).
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DMOG
Dangerous GoodsCAS number:89464-63-1 molecular formula:C6H9NO5
overview
compound introduction
Specs
| Chinese alias | 二甲基草酰甘氨酸 | N-(甲氧氧乙烯)-甘氨酸甲酯 | N-[甲氧基(氧代)乙酰基]甘氨酸甲酯 | ||
| English alias | AS-40798 | methyl N-(2-methoxy-2-oxoacetyl)glycinate | methyl n-[methoxy(oxo)acetyl]glycinate | Glycine, N-(methoxyoxoacetyl)-, methyl ester | methyl 2-((2-methoxy-2-oxoethyl)amino)-2-oxoacetate | methyl 2-[(2-methoxy-2-oxoethyl)amino]-2-oxoacetate | 2-(m | ||
| CAS number | 89464-63-1 | molecular formula | C6H9NO5 |
| molecular weight | 175.14 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 81.700 Ų | logp | -0.300 |
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
WGK Germany:
3
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