S-亚硝基谷胱甘肽(GSNO)是一种内源性氮氧化物,在肺和脑的细胞外液中高表达。 S-Nitrosoglutathione (GSNO), an amino acid nitric oxide donor, when under physiological conditions spontaneously releases nitric oxide. In research it has been observed to selectively inhibit platelet activation and display cardioprotective effects. This product also inhibits NF-κB activation, endothelial cell proliferation and cathepsin B (cysteine proteases). GNSO has demonstrated dose dependent effects on Thymocytes by inducing apoptosis in T cells in low concentrations ( S-亚硝基谷胱甘肽(GSNO)已用作: • 作为反相色谱的标准品,与化学蒸汽发生和原子荧光检测器(RPC-CVGAFS)和反相色谱荧光(RPC-FD)相结合。 • 作为分光光度法和高效液相色谱(HPLC)测定的标准品。 A spontaneously releasing nitric oxide donor which inhibits NFκB and platelet activation. S-Nitrosoglutathione (GSNO) is an endogenous nitrogen oxide and is highly distributed in extracellular fluids of the lung and brain. S-Nitrosoglutathione (GSNO), an amino acid nitric oxide donor, when under physiological conditions spontaneously releases nitric oxide. In research it has been observed to selectively inhibit platelet activation and display cardioprotective effects. This product also inhibits NF-κB activation, endothelial cell proliferation and cathepsin B (cysteine proteases). GNSO has demonstrated dose dependent effects on Thymocytes by inducing apoptosis in T cells in low concentrations ( S-Nitrosoglutathione (GSNO) has been used: • as a standard in reversed phase chromatography coupled to chemical vapour generation and atomic fluorescence detector (RPC-CVGAFS) and reversed phase chromatography fluorimetric (RPC-FD). • as a standard in spectrophotometric and high-performance liquid chromatography (HPLC) assay. A spontaneously releasing nitric oxide donor which inhibits NFκB and platelet activation.
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S-Nitrosylglutathione
Dangerous GoodsCAS number:57564-91-7 molecular formula:C10H16N4O7S
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | (2S)-2-amino-5-[[(1R)-2-(carboxymethylamino)-1-(nitrososulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid | CCRIS 2095 | SR-01000946622-1 | N-(N-L-gamma-glutamyl- S-Nitroso-L-cysteinyl)glycine | S-Nitrosoglutathione, >=97% | HY-D0845 | EN300-221929 | | ||
| CAS number | 57564-91-7 | molecular formula | C10H16N4O7S |
| molecular weight | 336.32 g/mol | Exact mass | ≥95% |
| PSA | 214.000 Ų | logp | -4.800 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移
WGK Germany:
3
Personal protective equipment:
dust mask type N95 (US), Eyeshields, Gloves
RTECS:
MC0558000
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
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