植物来源有豆科植物鹰嘴豆(Cicer arietinum L.)种子的胚芽部分，红车轴草(Trifolium pretense L.)全草等。 鹰嘴豆芽素A(Biochanin A)是一种异黄酮类植物雌激素，发现于红三叶草（红三叶）中，是ER -β选择性雌激素受体激动剂，可能具有预防乳腺癌的化学预防功效。鹰嘴豆芽素A也是芳香烃受体（AhR）的配体。它可以减少阻力，通过对钾和/或钙离子通道的影响微提高循环功能。具有雌激素样作用，能抑制胆固醇的升高，还具有抗真菌和抗肿瘤作用。对人体内的激素水平具有双向调节作用。还有抗癌解痉降血脂作用。 Biochanin A, an isoflavone, is a natural plant phytoestrogen which has been reported to be an antiproliferative and anti-inflammatory agent. Studies show that this compound inhibits iNOS expression and lipopolysacharide (LPS)-induced nitric oxide production in macrophages. Additionally, Biochanin A displays the ability to block phosphorylation of IκBα and p38 MAPK, which prevents NF-κB activation. Furthermore, Biochanin A has been observed to suppress IL-6, IL-1β, and TNF-α production.
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Biochanin A
Dangerous GoodsCAS number：491-80-5 molecular formula：C16H12O5
overview
compound introduction
Specs
| Chinese alias | 鹰嘴豆素A | 5,7-二羟基-4'-甲氧基异黄酮 | ||
| English alias | 5,7-Dihydrox -4'-methoxyisoflavone | B4098 | IDI1_001027 | KBio1_001027 | NCGC00017369-01 | Opera_ID_621 | Tox21_302901 | NCGC00022428-04 | NSC 123538 | Q-100552 | Spectrum3_001098 | KBio2_000675 | SPBio_000173 | Tox21_202097 | KBioSS_000675 | NCGC0001736 | ||
| CAS number | 491-80-5 | molecular formula | C16H12O5 |
| molecular weight | 284.26 g/mol | Exact mass | - |
| PSA | 76.000 Ų | logp | 3.000 |
numbering system
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physicochemical properties
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Safety information
WGK Germany：
3
Personal protective equipment：
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
Production methods and uses
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Related
upstream information
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MSDS
Found 1 shareMSDS
491-80-5 | Biochanin A.pdf
