CAS number：147859-80-1 molecular formula：C19H31N3O6
CA-074 methyl ester 是CA-074的细胞渗透性类似物，可作为不可逆的组织蛋白酶B抑制剂。据报道，CA-074甲酯在啮齿动物模型中抑制骨再吸收，并显示出在体外抑制B16黑素瘤细胞的侵袭。 介绍： CA-074 methyl ester 是一种特异性的 Cathepsin B 抑制剂，具有保护神经，抗癌、抗炎等多种生物活性。 用途： 使用CA-074甲酯用作心肌细胞、HeLa细胞和胰腺癌PANC-1细胞中的组织蛋白酶B抑制剂。 CA-074 methyl ester is a cell-permeable analog of CA-074 that acts as an irreversible cathepsin B inhibitor. CA-074 methyl ester is reported to inhibit bone reabsorption in rodent models and shown to inhibit B16 melanoma cell invasion|in vitro|.
| Chinese alias | CA-074甲酯 | ||
| English alias | Bio2_000234 | HMS3886D15 | SCHEMBL1974424 | AKOS027251055 | KBio3_000467 | 1-bromo-4-formylbenzene | CA-074(OMe) | HY-100350 | HMS1361L16 | CA-074 methyl ester | EX-A1196 | NCGC00163431-01 | DTXSID50881386 | CA074Me | CA-074Me | CA-074-Me | MFCD00797532 | | ||
| CAS number | 147859-80-1 | molecular formula | C19H31N3O6 |
| molecular weight | 397.47 g/mol | Exact mass | ≥97% |
| PSA | 117.000 Ų | logp | 1.200 |
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