NAc-Asp-Glu-Val-Asp-pNA;Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. It is also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. The sequence is based on PARP (poly(ADPribose) polymerase) cleavage site Asp216 for caspase-3. Cleavage is monitored colorimetrically at 405nm.A colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases NAc-Asp-Glu-Val-Asp-pNA;Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. It is also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. The sequence is based on PARP (poly(ADPribose) polymerase) cleavage site Asp216 for caspase-3. Cleavage is monitored colorimetrically at 405nm. A colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases
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N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
CAS number：189950-66-1 molecular formula：C26H34N6O13
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compound introduction
Specs
| Chinese alias | N-乙酰基-Asp-Glu-Val-Asp p-硝基苯胺 | ||
| English alias | Ac-DEVD-pNA | ||
| CAS number | 189950-66-1 | molecular formula | C26H34N6O13 |
| molecular weight | 638.58 g/mol | Exact mass | ≥97%(HPLC) |
| PSA | 303.000 Ų | logp | -1.400 |
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