白藜芦醇是一种在葡萄皮和其他植物中发现的酚类植物抗毒素。这种成分具有胞内抗氧化活性，可激活烟酰胺腺嘌呤二核苷酸(NAD+)依赖性组蛋白脱乙酰基酶1 (SIRT1)，参与线粒体生物发生、增强过氧化物酶体增殖物激活受体γ共激活因子-1a (PGC-1a)和FOXO（叉头框）活性。白藜芦醇的抗糖尿病、神经保护和抗脂肪形成作用可能是通过SIRT1的激活而介导的。白藜芦醇对单纯疱疹病毒-1 (HSV1)和HSV2具有抗病毒作用。此外，它还具有抗肿瘤和植物雌激素生物活性。目前确知白藜芦醇可通过介导几种生理事件，延长许多物种的寿命。 应用 COX-1 选择性抑制剂。 白藜芦醇已用于： 包封实验 研究其对Ca2+/钙调蛋白依赖性蛋白激酶II的糖尿病诱导激活介导的视网膜神经元细胞死亡的神经保护作用 用作体内荧光法评估葡萄叶stilbene含量的标准品 Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide (NAD+)-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-g-activated receptor coactivator-1a (PGC-1a) and FOXO (forkhead box) activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation. Resveratrol has antiviral action against Herpes simplex virus-1 (HSV1) and HSV2. It also exhibits antitumor and phytoestrogenic biological activities. Resveratrol is known to prolong life in many species by mediating several physiological events. Application Resveratrol has been used: in entrapment experiment to study its neuroprotective effect on retinal neuronal cell death mediated by diabetes-induced activation of Ca2+/calmodulin-dependent protein kinase II[2] as a standard in the assessment of stilbene content in grapevine leaf by in vivo fluorometry Selective inhibitor of COX−1.
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Resveratrol
Dangerous GoodsCAS number：501-36-0 molecular formula：C14H12O3
overview
compound introduction
Specs
| Chinese alias | 芪三酚 | 3,4',5-三羟基芪 | 3,4',5-三羟基-反式-二苯乙烯 | 5-[(1E)-2-(4-羟基苯基)乙烯基]-1,3-苯二酚 | (E)-5-[2-(4-羟苯基)-乙烯基]-1,3-苯二酚 | 反式-1,2-(3,4',5-三羟基二苯基)乙烯； 虎杖甙元 | ||
| English alias | Q369O8926L | CHEBI:27881 | CU-01000001503-3 | HMS1792H15 | NSC133100 | BPBio1_000479 | NCGC00344093-09 | RESVERATROL (MART.) | MLS000069735 | MLS001076538 | Stilbene, 2f | (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol | MLS002222231 | TaxusChinensisi | ||
| CAS number | 501-36-0 | molecular formula | C14H12O3 |
| molecular weight | 228.24 g/mol | Exact mass | - |
| PSA | 60.700 Ų | logp | 3.100 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H319: 引起严重眼睛刺激
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECS：
CZ8987000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
501-36-0 | Resveratrol | Resveratrol
