compound introduction
Indomethacin farnesil 是具有口服活性的、Indomethacin 的前体药物。Indomethacin (Indometacin) 是一种有效的，可透过血脑屏障的，非选择性的 COX1 和 COX2 抑制剂，在 CHO 细胞中，对人 COX-1 和 COX-2 的 IC50 值分别为 18 nM 和 26 nM。Indomethacin 通过干扰溶酶体的正常功能来破坏自噬流 (autophagic flux)。
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Indometacin Farnesil
Dangerous GoodsCAS number：85801-02-1 molecular formula：C34H40ClNO4
overview
Specs
| Chinese alias | 吲哚美辛法尼酯 | ||
| English alias | indometacin-farnesil | INDOMETACIN FARNECYL ESTER [WHO-DD] | Indometacin farnesil [JAN] | CAS-85801-02-1 | Indometacin farnesil (JAN) | SR-01000945050-1 | E 0710 | UNII-MB2386WGG8 | indometacin farnesil | I0943 | Infree (TN) | INDOMETACIN FARNECYL ESTER | | ||
| CAS number | 85801-02-1 | molecular formula | C34H40ClNO4 |
| molecular weight | 562.15 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 57.500 Ų | logp | 9.800 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
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MSDS
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