CAS number：790299-79-5 molecular formula：C28H30N6OS
Masitinib (AB1010)是一种新型的Kit和PDGFRα/β抑制剂，IC50分别为200 nM和540 nM/800 nM，但对ABL和c-Fms抑制作用较弱。Phase 3A tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor. Masitinib is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3. A tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor.
| Chinese alias | 马赛替尼 | ||
| English alias | 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE | Masitinib (AB1010) | Masitinib [INN] | Masatinib | Masitinib | A839556 | AKOS025312306 | DB11526 | HMS3244J12 | Mastinib | GTPL5656 | MASITINIB [WH | ||
| CAS number | 790299-79-5 | molecular formula | C28H30N6OS |
| molecular weight | 498.65 g/mol | Exact mass | - |
| PSA | 102.000 Ų | logp | 4.3 |
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