格氏试剂通常以溶液的形式使用，一般呈现为浅灰色至浅棕色透明溶液。它们一般以烷基卤化镁(RMgX)和二烷基镁(R2Mg)的中间态存在，是和复杂组分形成的平衡态混合物 (称为“Schlenk平衡”)。 其中的一些种类可能由于溶解度降低而产生沉淀，但这并不会影响它们的实际使用。 当出现沉淀时，请轻轻地摇晃瓶子使悬浮物充分分散后使用（如果沉淀物的量非常少，您可以使用悬浮液的上层清液）。特别是在冬天等寒冷的条件下，可能经常生成大量沉淀物。这种情况下，请用干燥的玻璃棒捣碎后使用。另外，您也可以将瓶子放进塑料袋后浸入40℃的水浴中使固体溶解(加热需要专业人员来操作，以防有安全隐患，请注意瓶子开启时有机溶剂的挥发）。 3-Chlorophenylmagnesium bromide (o-chlorophnylmagnesium bromide) is a Grignard reagent that can be used to synthesize: · 2,3-Di(o-chlorophenyl)buta-1,3-dienes by reacting with 1,4-dimethoxy 2-butyne in the presence of a copper(I) salt. · 2-Bromo-5-chlorothiophen-3-yl-(3-chlorophenyl)methanol by reacting with 2-bromo-5-chlorothiophene-3-carbaldehyde. · 2-(3-Chlorophenyl)-1-phenyl-1H-inden-1-ol from 2- benzoylbenzonitrile as a starting a material 3-Chlorophenylmagnesium bromide (o-chlorophnylmagnesium bromide) is a Grignard reagent that can be used to synthesize: · 2,3-Di(o-chlorophenyl)buta-1,3-dienes by reacting with 1,4-dimethoxy 2-butyne in the presence of a copper(I) salt. · 2-Bromo-5-chlorothiophen-3-yl-(3-chlorophenyl)methanol by reacting with 2-bromo-5-chlorothiophene-3-carbaldehyde. · 2-(3-Chlorophenyl)-1-phenyl-1H-inden-1-ol from 2- benzoylbenzonitrile as a starting a material
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3-Chlorophenylmagnesium bromide
Dangerous GoodsCAS number：36229-42-2 molecular formula：C6H4BrClMg
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 3-Chlorophenylmagnesium bromide 0.5 M in Tetrahydrofuran | 3-Chlorophenylmagnesium bromide, 0.5 M in THF | 3-chlorophenyl magnesium bromide | 3-chloro-phenyl magnesium bromide | 3-Chlorophenylmagnesium bromide, 1.0 M in 2-MeTHF | 3-Chlorophenylmagnesium b | ||
| CAS number | 36229-42-2 | molecular formula | C6H4BrClMg |
| molecular weight | 215.76 g/mol | Exact mass | 0.5M solution in THF |
| PSA | 0.000 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08 , GHS07 , GHS02
Signal word：
Danger
Hazard Statement：
H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H351: 怀疑引起遗传缺陷 H225: 高度易燃的液体和蒸气
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。 P281: 根据需要使用个人防护设备。
WGK Germany：
3
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
36229-42-2 | 3-Chlorophenylmagnesium bromide.pdf
