紫草素是从紫草根中提取的一种主要的植物化学成分。它是一种天然蒽醌衍生物。 应用 紫草素已被用于：增强吉非替尼对野生型肺癌细胞酪氨酸激酶受体表皮生长因子受体(EGFR)的抗肿瘤活性；用作肾脏需氧糖病的抑制剂；作为抗炎剂，以测试其改善脂多糖(LPS)诱导的心功能障碍的作用；刺激骨髓源性巨噬细胞(BMDM)，检测干扰素调节因子1对细胞死亡的影响。 Shikonin is a major phytochemical compound extracted from the roots of Lithospermum erythrorhizon. It is a natural anthraquinone derivative. Application： Shikonin has been used： to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells； as an inhibitor of renal aerobic glycosis and a potential； as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction； to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death
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Shikonin
Dangerous GoodsCAS number：517-89-5 molecular formula：C16H16O5
overview
compound introduction
Specs
| Chinese alias | (±)-Alkannin | (±)-Shikalkin | (±)-Shikonin | (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone | 紫草宁 | (±)-5,8-二羟基-2-(1-羟基-4-甲基-3-戊烯基)-1,4-萘醌 | (±)-紫草宁 | (±)-紫草素 | ||
| English alias | 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione | Shikonin S | (+)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone | 2-(2-methoxyethoxyl)ethyl 4-methylbenzenesulfonate | shikonin | AS-13554 | BRN 2058010 | C.I | ||
| CAS number | 517-89-5 | molecular formula | C16H16O5 |
| molecular weight | 288.30 g/mol | Exact mass | 分析标准品 |
| PSA | 94.800 Ų | logp | 3.000 |
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physicochemical properties
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Safety information
Hazard Statement：
H412: 对水生生物有害并具有长期持续影响
Statement of Preventive Measures：
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。
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MSDS
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