无气味,有吸湿性。溶于水， 溶液呈黄红色，并带极强的黄绿色荧光，酸化后消失，中和或碱化后又出现，微溶于乙醇，几乎不溶于氯仿和乙醚。水溶液与血浆等渗。荧光素是一种黄嘌呤染料，是生物学中常用的标记试剂。水溶性荧光染料由于其分子半径小，渗透性和血管灌注研究中得到应用。 以荧光素钠作为荧光示踪剂，用于研究血脑屏障(BBB)和血脊髓屏障(BSCB)在啮齿类动物模型中的通透性。以该染料为探针底物，研究了有机阴离子转运多肽(OATP)介导的肝细胞药物转运。荧光素钠还被应用于光致退色后 原位 溶质通过荧光恢复进入骨内。 荧光素钠盐被用作一种溶质，用于研究微血管渗透性。它已被用作研究血液屏障穿透性的测试分子。 Fluorescein is a xanthene dye and is a common labeling agent in biology. Fluorescein sodium salt has been used as a solute to study microvessel permeability.It has been used as a test molecule to study blood barrier penetration. Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius.Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models.The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes.Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).
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Fluorescein sodium salt
Dangerous GoodsCAS number：518-47-8 molecular formula：C20H10Na2O5
overview
compound introduction
Specs
| Chinese alias | 黄色8号 | 酸性黄 73 | 荧光黄二钠盐 | 荧光素钠盐 | ||
| English alias | Acid Yellow 73 | Uranine | C.I. 45350 | NaFl | NaFluo | Yellow No. 8 | D&C | ||
| CAS number | 518-47-8 | molecular formula | C20H10Na2O5 |
| molecular weight | 376.27 g/mol | Exact mass | AR |
| PSA | 81.700 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
Signal word：
Warning
Hazard Statement：
H319: 引起严重眼睛刺激
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
WGK Germany：
1
Personal protective equipment：
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS：
LM5425000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
