Dequalinium Chloride 是 Apamin (HY-P0256) 敏感型的钾离子通道选择性阻断剂。Dequalinium Chloride 是一种阳离子、亲脂性线粒体毒物。 Dequalinium chloride is an Apamin (HY-P0256)-sensitive potassium channel selective blocker. Dequalinium chloride is a cationic, lipophilic mitochondrial poison. Dequalinium Chloride is a PKC inhibitor with an IC50 of 7-18 μM as well as a selective bee venom peptide-sensitive potassium channel blocker with an IC50 of 1.1 μM. Application： Dequalinium chloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC). These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
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Dequalinium Chloride
Dangerous GoodsCAS number：522-51-0 molecular formula：C30H40Cl2N4
overview
compound introduction
Specs
| Chinese alias | 1,1'-(癸烷-1,10-二基)双(4-氨基-2-甲基喹啉-1-ium) 氯化物 | 地喹氯胺 | 克菌定 | ||
| English alias | 1,1'-(Decane-1,10-diyl)bis(4-amino-2-methylquinolin-1-ium) chloride | 1,1′-Decamethylenebis(4-aminoquinaldinium) dichloride | Dequafungan | Decabis | Danical | ||
| CAS number | 522-51-0 | molecular formula | C30H40Cl2N4 |
| molecular weight | 527.57 g/mol | Exact mass | - |
| PSA | 59.800 Ų | logp | - |
numbering system
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physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
警告
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
522-51-0 | Dequalinium chloride.pdf
