CAS number：76-78-8 molecular formula：C22H28O6
Quassin (Nigakilactone D) 是一种从 Quassia amara 的茎皮提取物中提取的生物活性三萜。Quassin 抑制 P. falciparum，IC50 为 0.15 μM。Quassin 具有可逆的避育能力，抗雌激素和抗疟原虫活性。 Nissin (Nigakilactone D) is a bioactive triterpenoid extracted from the stem bark of Nissin amara. Massin inhibits P. falciparum with an IC50 of 0.15 μ M. Quasin has reversible fertility avoidance ability, anti estrogen and anti malaria activity.
| Chinese alias | 苦楝树甙 | 抗感染 | ||
| English alias | AKOS032948714 | QP1YAK6QGK | C08778 | E88800 | (3AS,6aR,7aS,8S,11aS,11bS,11cS)-1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-2,10-dimethoxy-3,8,11a,11c-tetramethyldibenzo(de,g)chromene-1,5,11-trione | LMPR0106110002 | QUASSIN [INCI] | QUASSIN [MI] | NSC 3 | ||
| CAS number | 76-78-8 | molecular formula | C22H28O6 |
| molecular weight | 388.5 | Exact mass | ≥98% |
| PSA | 78.9 | logp | 2.4 |
| CAS | 76-78-8 |
| HMDB ID | HMDB0036587 |
| Wikidata | Q105116871 |
| NSC Number | NSC Number: NSC36342 |
| PubChem CID | 4998 |
| Nikkaji Number | J181.311K |
| DSSTox Substance ID | DTXSID30861626 |
| PubChem Reference Collection SID | 518150158 |
| XLogP3 | XLogP3-AA: 2.4 |
| 熔点 | 221 - 222 °C |
| 复杂性 | 838 |
| Exact Mass | 388.18858861 |
| 形式电荷 | 0 |
| 物理描述 | 固体 |
| 重原子计数 | 28 |
| Molecular Weight | 388.5 |
| Monoisotopic Mass | 388.18858861 |
| 可旋转键计数 | 2 |
| 氢键供体计数 | 0 |
| 氢键受体计数 | 6 |
| 共价键单元计数 | 1 |
| 同位素原子计数 | 0 |
| 拓扑极性表面积 | 78.9 Ų |
| 定义键立体中心计数 | 0 |
| 定义原子立体中心计数 | 0 |
| 未定义键立体中心计数 | 0 |
| 未定义原子手性中心计数 | 7 |
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