麦斯明是一种次要的烟草生物碱,已显示通过吡啶基氧代丁基化作用对DNA造成损伤,对细胞具有遗传毒性作用。研究表明,在细胞中,肌苷可以被H | 2 | O | 2 |和3-吗啉代亚砜亚胺活化为反应性中间体。已知肌氨酸在酸性pH下经历环链互变异构,并以氨基酮形式存在。此外,Myosmine是用于监测烟草烟雾对细胞影响的理想工具。 Product Description Myosmine is a minor tobacco alkaloid which has been shown to possess genotoxic effects on cells through DNA damage by pyridyloxobutylation. Studies indicate that in cells Myosmine can be activated into reactive intermediates by H|2|O|2| and 3-morpholinosydnonimine . It is known that under acidic pH Myosmine undergoes a ring-chain tautomerism and is present in the amino-keto form. Furthermore, Myosmine is an ideal tool to use to monitor the effects of tobacco smoke on cells. Product Application Nitrosation reactions;Peroxidation reaction with hydrogen peroxide
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Myosmine
Dangerous GoodsCAS number:532-12-7 molecular formula:C9H10N2
overview
compound introduction
Specs
| Chinese alias | 3-(1-吡咯啉-2-基)吡啶 | ||
| English alias | 9O0A545W4L | HY-W001909 | Pyridine, 3-(1-pyrrolin-2-yl)- | BPBio1_000719 | Prestwick2_000647 | 3-(1-Pyrrolin-2-yl)pyridine, 8CI | BDBM50125053 | KBio2_004178 | STL554354 | 1-AMINO-CYCLOPENT-3-ENECARBOXYLICACID | 3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine, 9CI | ||
| CAS number | 532-12-7 | molecular formula | C9H10N2 |
| molecular weight | 146.19 g/mol | Exact mass | 10mM in DMSO |
| PSA | 25.300 Ų | logp | 0.600 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水
RTECS:
UT7660000
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
532-12-7 | NICOTINE RELATED COMPOUND D, UNITEDSTATES PHARMACOPEIA (USP) REFERENCESTANDARD.pdf





