溶于苯、乙醇、乙醚等大多数有机溶剂，不溶于水，和水反应。对潮湿敏感，皮肤接触可引起过敏。二氯甲烷溶解度：1G / 10ML。脱氢偶联试剂，修饰小牛心线粒体脱氢转移酶；抑制F1F0-ATPase和其它的质子转移酶。 多肽合成试剂。 DCC是 N,N′-二环己基碳二亚胺的首字母缩写。在肽合成中，它被用来活化羧基。DCC的结构已通过红外光谱和拉曼光谱得到了分析。它介导聚乙烯醇与游离乙酰丙酸的酯化反应生成聚乙烯醇-co乙酰丙酸酯 用途： DCC可用于促进 7-(叔-丁基二甲基硅基)氧与丙酸的酯化反应生成7-(叔-丁基二甲基硅基)氧庚-2,4-二炔-1-醇。 还可用于合成： 通过2-苯乙烯基和2-(4-硝基苯基)异硫氰酸酯[2+2]环加成合成:1,3-噻唑烷衍生物。 1,3,5-恶二嗪-4-硫酮与苯甲酰异硫氰酸酯[4+2]环加成反应。 在芳香族(或异芳香族)羧酸存在下，通过与(N-异环氨基)三苯基磷烷反应，生成空间位阻的1,3,4-恶二唑衍生物。 DCC已可用于制备钛酸盐纳米管-酞菁(TiONts-Pc)纳米复合材料和7-(叔-丁基二甲基硅基)氧)庚-2,4-二炔-1-丙酸酯。 肽合成羧基激活剂 Carboxy group activating reagent for peptide synthesis DCC is the acronym for N,N′-dicyclohexylcarbodiimide. In peptide synthesis, it is utilized for the activation of carboxyl group. The structure of DCC has been analyzed based on IR and Raman spectral data.It mediates the esterification of poly(vinyl alcohol) with free levulinic acid to form poly(vinyl alcohol-co-vinyl levulinate) Application： Carboxy group activating reagent for peptide synthesis. DCC has been used in the preparation of titanate nanotubes-phthalocyanine(TiONts-Pc) nanohybrids and 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-yl propynoate. DCC may be used to promote the esterification of 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-ol with propiolic acid to form 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-yl propynoate. It can also used to synthesize: 1,3-Thiazetedine derivatives via [2+2] cycloaddition with 2-phenylethenyl- and 2-(4-nitrophenyl)ethenyl isothiocyanates 1,3,5-Oxadiazine-4-thiones via [4+2] cycloaddition with benzoyl isothiocyanates. Sterically hindered 1,3,4-oxadiazole derivatives by reacting with (N-isocyanimino)triphenylphosphorane in the presence of aromatic (or heteroaromatic) carboxylic acids
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N,N′-Dicyclohexylcarbodiimide
Dangerous GoodsCAS number：538-75-0 molecular formula：C13H22N2
overview
compound introduction
Specs
| Chinese alias | 二环己基碳二亚胺 | ||
| English alias | DCC | EC 208-704-1 | STL089892 | 1,3-dicyclohexylcarbodimide | N,N'-Methanetetraylbiscyclohexaamine | US8815951, N/A | AI3-08191 | DCC | dicyclohexyl carbodimide | dicyclohexylcarbod iimide | NSC53373 | NSC-53373 | 1, 3-dicyclohexylcarbodiimide | DICYCLOH | ||
| CAS number | 538-75-0 | molecular formula | C13H22N2 |
| molecular weight | 206.33 g/mol | Exact mass | ≥99% |
| PSA | 24.700 Ų | logp | 4.700 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS06 , GHS05
Signal word：
Danger
Hazard Statement：
H311: 皮肤接触有毒 H302: 吞食有害 H318: 造成严重的眼睛损伤 H317: 可能引起皮肤过敏反应
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P272: 被污染的工作服不允许离开工作场所 P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。 P362+P364: 脱掉沾污的衣服，清洗后方可
WGK Germany：
1
Personal protective equipment：
Faceshields,full-face respirator (US),Gloves,Goggles,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter
RTECS：
FF2160000
UN Number：
2811
Packing Group：
Ⅰ
Production methods and uses
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upstream information
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downstream information
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MSDS
Found 1 shareMSDS
538-75-0 | DCC.pdf
