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SPDP (Succinimidyl 3-[2-pyridyldithio] propionate)

Dangerous Goods

CAS number:68181-17-9    molecular formula:C12H12N2O4S2

overview

compound introduction

SPDP crosslinker, N-Succinimidyl 3-(2-pyridyldithio) propionic acid, also called N-succinimidyl 3-(2-pyridyldithio)-propionate, or OPSS-NHS, is a short-length crosslinker for amine to sulfhydryl (thiol) conjμgation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups. Nanocs LC-SPDP is a long-length crossliker for amine to sulfhydryl conjμgation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups.3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is useful for the preparation of enzyme immunoconjμgates and hapten carrier molecule conjμgates. It has been used for antibody conjμgation and as a protein cross-linker. SPDP crosslinker, N-Succinimidyl 3-(2-pyridyldithio) propionic acid, also called N-succinimidyl 3-(2-pyridyldithio)-propionate, or OPSS-NHS, is a short-length crosslinker for amine to sulfhydryl (thiol) conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups. Nanocs LC-SPDP is a long-length crossliker for amine to sulfhydryl conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups. 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. It has been used for antibody conjugation and as a protein cross-linker.

Specs

Chinese alias3-(2-吡啶基二硫基)丙酸N-羟基琥珀酰亚胺酯
English alias(SPDP);N-Succinimidyl 3-[2-pyridyldithio]propionate | 1-(1-Oxo-3-(2-pyridyldithio)propoxy)pyrrolidine-2,5-dione | 2,5-Pyrrolidinedione, 1-(1-oxo-3-(2-pyridinyldithio)propoxy)- | SPDP (2mg*5) | 3-(2-Pyridyldithio)propionic Acid N-Succinimidyl Ester | 3-(Py
CAS number68181-17-9molecular formulaC12H12N2O4S2
molecular weight312.36 g/molExact mass≥95%
PSA127.000 Ųlogp0.700

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

Found 1 shareMSDS
68181-17-9 | 1-[1-oxo-3-(2-pyridyldithio)propoxy]pyrrolidine-2,5-dione.pdf