苯基次膦酸乙酯是一种有机磷化合物。在钯-1,2-双（二苯基膦基）乙烷络合物（催化剂）的存在下，它可与末端炔烃进行区域选择性的Markovnikov加成反应。 苯基次膦酸乙酯是Inezin（S-苄基-O-乙基苯基膦硫醇盐）在紫外照射下的光分解产物。 它可以通过在吡啶存在下使次膦酸与氯甲酸乙酯反应来制备。 使用 乙基三甲基甲硅烷基苯基亚膦酸酯或相应的三甲基锡烷基酯对其进行乙基化已有报道。据报道，它可以在保持构型的情况下与乙烯进行自由基加成。 苯基次膦酸乙酯可用于制备以下种类的二乙基咪唑-2-基-（氨基）甲基膦酸酯和次膦酸酯： • 咪唑-2-基甲基（N-丁基氨基）膦酸酯二乙酯 • 咪唑-2-基甲基（N-苄氨基）膦酸酯二乙酯 • 咪唑-2-基甲基（N-丁基氨基）苯基次膦酸酯乙酯 • 咪唑-2-基甲基（N-苄氨基）苯基次膦酸酯乙酯 Ethyl phenylphosphinate is an organophosphorous compound. It undergoes regioselective Markovnikov addition reaction with terminal alkynes in the presence of palladium-1,2-bis(diphenylphosphino)ethane complex (catalyst). Ethyl phenylphosphinate is the photodecomposition product of Inezin (S-benzyl O-ethyl phenylphosphonothiolate) on the ultraviolet irradiation. It can be prepared by the reaction of phosphinic acid with ethyl chloroformate in the presence of pyridine. Its ethylation using ethyl trimethylsilyl phenylphosphonite or the corresponding trimethylstannyl ester has been described. Its free-radical addition to ethylene has been reported to proceed with the retention of configuration. Ethyl phenylphosphinate may be used in the preparation of the following diethyl imidazol-2-yl-(amino) methylphosphonates and phosphinates: • imidazol-2-yl-methyl(N-butylamino)phosphonate diethyl ester • imidazol-2-yl-methyl(N-benzylamino)phosphonate diethyl ester • imidazol-2-yl-methyl(N-butylamino)phenylphosphinate ethyl ester • imidazol-2-yl-methyl(N-benzylamino)phenylphosphinate ethyl ester
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Ethyl phenylphosphinate
CAS number：2511-09-3 molecular formula：C6H5P(O)H(OC2H5)
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Specs
| Chinese alias | 苯膦酸乙酯 | ||
| English alias | Phosphinic acid, ethyl ester | WLN: OPHR&O2 | NSC 300841 | NSC300841 | NSC-300841 | ethoxy-oxo-phenylphosphanium | AKOS027325270 | Phosphinic acid, phenyl-, ethyl ester | O-Ethyl phenylphosphinate | J-015815 | AS-63911 | Phosphinic acid, P-phenyl-, ethyl | ||
| CAS number | 2511-09-3 | molecular formula | C6H5P(O)H(OC2H5) |
| molecular weight | 170.15 g/mol | Exact mass | ≥94% |
| PSA | 26.300 Ų | logp | 1.600 |
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2511-09-3 | Ethyl phenylphosphinate.pdf
