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β-Nicotinamide Mononucleotide (NMN)

Dangerous Goods

CAS number:1094-61-7    molecular formula:C11H15N2O8P

overview

compound introduction

β-烟酰胺单核苷酸(NMN)用于研究过RNA适体的结合基元,和包含了β烟酰胺单核苷酸 (β-NMN)-活化RNA片段的核酸酶活化过程。 β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. A product of the eNAMPT reaction and a NAD+ intermediate β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments. β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

Specs

Chinese aliasβ-烟酰胺核糖单磷酸, 烟酰胺-1-ium-1-β-D-呋喃糖苷5'-磷酸, 烟酰胺核苷酸 | β-烟酰胺核糖单磷酸盐 | β-烟酰胺单核苷酸
English aliasAfAE'Adaggeratrade markAfA centA centasA notA em leaderA inverted exclamation mark-Nicotinamide mononucleotide | CCG-267847 | nicotinamide ribonucleotide | NMN zwitterion | beta-Nicotinamide mononucleotide | .BETA.-D-NMN | C00455 | Nicotinamide ribotide |
CAS number1094-61-7molecular formulaC11H15N2O8P
molecular weight334.22 g/molExact mass10mM in Water
PSA166.000 Ųlogp-3.500

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Safety information

WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US)

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