Ethylhydrocupreine hydrochloride (Optochin hydrochloride) 是一种具有抗菌作用的奎宁衍生物,具有抗肺炎链球菌 (S. pneumoniae) 的活性。Ethylhydrocupreine hydrochloride 还具有抗 Plasmodium falciparum 的抗疟活性,IC50 为 25.75 nM。Ethylhydrocupreine hydrochloride 是一种 Gallus gallus 2 受体 (ggTas2r1,ggTas2r2 和 ggTas2r7) 激动剂。 Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a quinine derivate with antimicrobial activity against S. pneumoniae. Ethylhydrocupreine hydrochloride also possesses antimalarial activity against Plasmodium falciparum, with an IC50 of 25.75 nM. Ethylhydrocupreine hydrochloride is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist
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Ethylhydrocupreine hydrochloride
CAS number:3413-58-9 molecular formula:C21H29ClN2O2
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| Chinese alias | 乙氢去甲奎宁盐酸盐 | 奥普托欣盐酸盐 | 乙基氢化铜蛋白 | 盐酸奥普托欣 | 乙基氢化铜盐酸盐 | ||
| English alias | Cinchonan-9-ol, 6'-ethoxy-10,11-dihydro-, monohydrochloride, (8.alpha.,9R)- | NSC 5361 | QNRATNLHPGXHMA-XZHTYLCXSA-N | GNF-Pf-5574 | Hydrocupreine, monohydrochloride | MFCD00135594 | NSC5361 | NSC-5361 | Hydrocupreine, hydrochloride | WLN: T66 BNJ HO2 EYQ | ||
| CAS number | 3413-58-9 | molecular formula | C21H29ClN2O2 |
| molecular weight | 376.92 g/mol | Exact mass | ≥98% |
| PSA | 45.600 Ų | logp | - |
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