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(DHQ)2PHAL

Dangerous Goods

CAS number:140924-50-1    molecular formula:C48H54N6O4

overview

compound introduction

配体,用于不饱和酯和三取代 C=C 键的非对称二羟基化。 Sharpless 不对称双羟基化的配体,用于由 (E,E)- 或 (E,Z)-1,3-二烯酸甲酯不对称制备 syn-3,5-羟基羧酸酯。 General description: DHQ)2PHAL is a modified cinchona alkaloid. application: (DHQ)2PHAL may be used in the following processes: As a catalyst Asymmetric and chemoselective N-allylic alkylation of indoles with Morita-Baylis-Hillman carbonates to form pyrrolo[1,2-a]indole and pyrrolo[3,2,1-ij]quinoline derivatives. As a ligand for the osmium catalyzed-Sharpless asymmetric dihydroxylation step of (S)-a-benzoyloxy carboxylic acids multistep synthesis. As a ligand for the carbamate based asymmetric aminohydroxylation of styrene derivatives to form N-carbamate protected R-arylglycinols.

Specs

Chinese alias-
English alias(3alpha)-6'-Methoxy-9-[(4-{[(4beta)-6'-methoxy-10,11-dihydrocinchonan-9-yl]oxy}phthalazin-1-yl)oxy]-10,11-dihydrocinchonan | (DHQ)2PHAL | (DHQ)2-PHAL | AD-mix alpha | BP-12219 | (8ALPHA,9R,8'''ALPHA,9'''R)-9,9'-[PHTHALAZINE-1,4-DIYLBIS(OXY)]BIS(6'-METHOXY
CAS number140924-50-1molecular formulaC48H54N6O4
molecular weight778.98 g/molExact mass≥95%
PSA95.000 Ųlogp8.800

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H317: 可能引起皮肤过敏反应
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P501: 将内容物/容器处理到。。。 P272: 被污染的工作服不允许离开工作场所 P333+P313: 如发生皮肤刺激或皮疹:求医/就诊。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。
WGK Germany:
3
Personal protective equipment:
Eyeshields,Faceshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

Production methods and uses

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upstream information

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downstream information

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MSDS

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