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Coenzyme A (lithium salt hydrate)

Dangerous Goods

CAS number:18439-24-2    molecular formula:C21H33N7O16P3S • XLi [XH2O]

overview

compound introduction

辅酶A(CoA)由磷酸泛酸酯在泛酸激酶的作用下合成,是主要的调节剂。 应用 辅酶A三锂盐用于: 生成乙酰转移酶Gcn5酰化动力学分析的标准曲线 作为 JNADH 和 JNADPH 生产分析中的辅助因子 标记 Alexa647(AF647)探针 Coenzyme A (CoA) is synthesized from phosphopantothenate by the action of enzyme pantothenate kinase and is the master regulator. Product Application Coenzyme A trilithium salt has been used: in standard curve generation in the kinetic assay of acetyltransferase Gcn5 acylation as a cofactor in JNADH and JNADPH production assay in the labeling of Alexa647 (AF647) probe Biochemical and physiological mechanisms Coenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes. Acyl CoA accumulation is implicated in metabolic disorders and may indirectly lead to the pathogenesis associated with carbon-induced mitochondrial stress heart failure, diabetes and obesity.

Specs

Chinese alias辅酶 A 锂盐
English aliasCoenzyme A (lithium salt) | CoA
CAS number18439-24-2molecular formulaC21H33N7O16P3S • XLi [XH2O]
molecular weight764.5(free basis) g/Exact mass≥95%
PSA356.000 Ųlogp-

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移

Production methods and uses

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MSDS

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