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2-Thiocytidine

CAS number:13239-97-9    molecular formula:C9H13N3O4S

overview

compound introduction

2-硫胞苷是从大肠杆菌| tRNA的水解物中分离出的核苷碱基。 2-Thiocytidine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成,诱导细胞凋亡 (apoptosis) 等 2-Thiocytidine is a nucleoside base that has been isolated from hydrolyzates of|Escherichia coli|tRNA. 2-thiactidine is a nucleoside base isolated from the hydrolysate of E. coli | tRNA; 2-Thiocytidine is a purine nucleoside analogue. Purine nucleoside analogues have extensive antitumor activity and target malignant tumors of the inert lymphatic system. The anti-cancer mechanism in this process depends on inhibition of DNA synthesis, induction of apoptosis, etc Application: 2-Thiocytidine is a cytidine analogue. A profiled metabolite in HFD-induced obese mice after oral administration of Huangjinya green tea extract.

Specs

Chinese alias2-硫代胞苷
English alias2-Thio-D-cytidine
CAS number13239-97-9molecular formulaC9H13N3O4S
molecular weight259.28 g/molExact mass≥98%
PSA144.000 Ųlogp-1.500

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