Sinefungin是病毒粒子mRNA (鸟嘌呤-7-)-甲基转移酶、 mRNA (核苷-2'-)-甲基转移酶和病毒增殖的有效抑制剂。Sinefungin 是一种 SET7/9 抑制剂,通过抑制H3K4甲基化来改善肾纤维化。 Sinefungin is a natural nucleoside analog of S-adenosylmethionine and inhibits Streptococcus pneumoniae biofilm growth. Its derivatives can be used as inhibitors and structure probes for human protein lysine methyltransferase SETD2.
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Sinefungin(A-9145)
Dangerous GoodsCAS number:58944-73-3 molecular formula:C15H23N7O5
overview
compound introduction
Specs
| Chinese alias | (2S,5S)-2,5-二氨基-6-[(2R,3S,4R,5R)-5-(6-氨基嘌呤-9-基)-3,4-二羟基氧杂兰-2-yl]己酸 | ||
| English alias | BRN 3574678 | Decofuranuronic acid, 6,9-diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-, (beta-D-ribo)- | LILLY 57926 | Sinefungine | TCA-O-PCP?Trichloroacetic acid pentachlorophenyl ester | LY-57926 | DB01910 | Q27093021 | 6,9-Diamino-1-(6-amino | ||
| CAS number | 58944-73-3 | molecular formula | C15H23N7O5 |
| molecular weight | 381.39 g/mol | Exact mass | - |
| PSA | 209.000 Ų | logp | -4.3 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
WGK Germany:
3
Personal protective equipment:
dust mask type N95 (US), Eyeshields, Gloves
RTECS:
HE3140000
Production methods and uses
No production method and use information yet
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upstream information
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downstream information
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MSDS
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