CAS number：124168-73-6 molecular formula：C23H34N6O6
4-氨基苯甲酰基-Gly-Pro-D-Leu-D-Ala异羟肟酸，也称为MMP抑制剂I，是MMP-1和MMP-8（胶原酶，IC | 50 | =1.0μM），MMP的广谱抑制剂-9（粒细胞明胶酶，IC | 50 | =50μM）和MMP-3（皮肤成纤维细胞溶血素，IC | 50 | =50μM）。 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid, also called MMP Inhibitor I, is a broad spectrum inhibitor of MMP-1 and MMP-8 (collgenases, IC|50|=1.0μM), MMP-9 (granulocyte gelatinase, IC|50|=50μM), and MMP-3 (skin fibroblast stromelysin, IC|50|=50μM).
| Chinese alias | - | ||
| English alias | 4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid | 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid | FN-439 | MMP-inhibitor I | SCHEMBL3394288 | HY-100210 | D-Alaninamide, N-(4-aminobenzoyl)glycyl-L-prolyl-D-leucyl-N-hydroxy- | NSC 727371 | | ||
| CAS number | 124168-73-6 | molecular formula | C23H34N6O6 |
| molecular weight | 490.6 | Exact mass | ≥95% |
| PSA | 183 | logp | 0.2 |
| CAS | 124168-73-6 |
| Wikidata | Q72438136 |
| PubChem CID | 4648 |
| DSSTox Substance ID | DTXSID40274440 |
| XLogP3 | XLogP3-AA: 0.2 |
| 复杂性 | 782 |
| Exact Mass | 490.25398283 |
| 形式电荷 | 0 |
| 重原子计数 | 35 |
| Molecular Weight | 490.6 |
| Monoisotopic Mass | 490.25398283 |
| 可旋转键计数 | 10 |
| 氢键供体计数 | 6 |
| 氢键受体计数 | 7 |
| 共价键单元计数 | 1 |
| 同位素原子计数 | 0 |
| 拓扑极性表面积 | 183 Ų |
| 定义键立体中心计数 | 0 |
| 定义原子立体中心计数 | 0 |
| 未定义键立体中心计数 | 0 |
| 未定义原子手性中心计数 | 3 |
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