Methyl pyruvate is a compound used in stimulus-secretion coupling. Studies indicate that Methyl pyruvate increases free calcium ion concentration in the cytosol of pancreatic cells. In addition, it is believed that Methyl pyruvate stimulates the production of ATP, which is supported by the fact that Methyl pyruvate depolarizes mitochondrial membrane potential, similar to glucose. Studies on Jurkat T-lymphocyte mitochondria show that Methyl pyruvate directly inhibits cation current across the membrane, which sμggests that this compound is not a mitochondrial substrate. Furthermore, the inhibition of the K(ATP) channels mediates the induction of electrical activity in pancreatic β cells.A compound used in stimulus-secretion coupling Description: Methyl pyruvate is a pyruvic ester. Surface conditions during Pt/silica EUROPT-1 modified by cinchonidine catalyzed by enantioselective hydrogenation of methyl pyruvate to R-(+)-methyl lactate were investigated. Enantioselective hydrogenation of methyl pyruvate over finely dispersed polyvinylpyrrolidone-stabilized and the corresponding alumina-supported iridium clusters modified with cinchonidine was studied. The molecular orientation and conformation of methyl pyruvate on Ni(111) surface has been investigated in the temperature range 105-220K. Methyl pyruvate is reported to stimulate insulin secretion in vitro and in vivo. Application: Methyl pyruvate may be used to investigate the adsorption and reactivity of methyl pyruvate on Pt{111}. It may be used in the preparation of dimethyl 2,3-dimethylenebutanedioate.
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Methyl pyruvate
Dangerous GoodsCAS number：600-22-6 molecular formula：C4H6O3
overview
compound introduction
Specs
| Chinese alias | 甲基丙酮酸酯 | 乙酰甲酸甲酯 | ||
| English alias | QSPL 174 | F1905-6998 | InChI=1/C4H6O3/c1-3(5)4(6)7-2/h1-2H | 2-oxopropionic acid methyl ester | 2-oxo-propionic acid methyl ester | Tox21_202853 | PYRORACEMIC ACID METHYL ESTER | NCGC00260399-01 | pyruvic acid methylester | Pyruvic acid, methyl ester | A | ||
| CAS number | 600-22-6 | molecular formula | C4H6O3 |
| molecular weight | 102.09 g/mol | Exact mass | ≥97%(GC) |
| PSA | 43.400 Ų | logp | 0.000 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS02
Signal word：
Warning
Hazard Statement：
H335: 可能引起呼吸道刺激 H318: 造成严重的眼睛损伤 H317: 可能引起皮肤过敏反应 H226: 易燃液体和蒸气
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P370+P378: 火灾时：使用干砂、干粉或抗醇泡沫灭火。 P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P233: 保持容器密闭。 P240: 地面/粘结容器和接收设备 P403+P235: 存放在通风良
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
600-22-6 | Methyl pyruvate.pdf
