Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects. In Vitro In Vero cells, Euparin shows antiviral activity against poliovirus types 1, 2, and 3 with EC 50 values of 0.47 µg/mL, 0.12 µg/mL, and 0.15 µg/mL, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Euparin (8, 16 and 32 mg/kg) reduces depression-like behavior in Chronic Unpredictable Mild Stress (CUMS) model of mice. All doses of Euparin are found to increase the contents of monoamine neurotransmitter and decrease monoamine oxidase and reactive oxygen species (ROS) levels in brain of depression mice. Euparin restores CUMS-induced decrease of Spermidine/Spermine N1-Acetyltransferase 1 (SAT1), N-methyl-D-aspartate receptor subtype 2B (NMDAR2B) and brain derived neurotrophic factor (BDNF) expression. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Euparin
CAS number：532-48-9 molecular formula：C13H12O3
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compound introduction
Specs
| Chinese alias | 优帕林 | ||
| English alias | 1-(6-Hydroxy-2-(prop-1-en-2-yl)benzofuran-5-yl)ethanone | KBio3_002178 | Spectrum3_001229 | E88715 | AKOS028108491 | BSPBio_002678 | KBioGR_001921 | Euparin | Spectrum2_000306 | 1-(6-Hydroxy-2-(1-methylethenyl)-5-benzofuranyl)ethanone | DivK1c_006242 | Q2 | ||
| CAS number | 532-48-9 | molecular formula | C13H12O3 |
| molecular weight | 216.23 g/mol | Exact mass | ≥99% |
| PSA | 50.400 Ų | logp | 3.6 |
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