水中溶解度: 100 g/l (25°C),溶于乙醇和醚,(R)-(-)-扁桃酸,一种手性拆分剂, 也被用作合成药物(如青霉素和头孢菌素)的结构单元。通过腈水解酶,它可以从(合成)R,S)-甘露腈进行高产率和对映选择性的合成。 (R)-(-)-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (R,S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme. R-(-)-Mandelic Acid is a synthetic intermediate commonly used for pharmaceutical synthesis. ;(R)-(-)-Mandelic acid has been used in studies to assess its ability to undergo spontaneous oscillatory chiral conversion and spontaneous condensation to form polymandelic acid.
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(R)-(-)-Mandelic acid
Dangerous GoodsCAS number:611-71-2 molecular formula:C8H8O3
overview
compound introduction
Specs
| Chinese alias | 扁桃酸 | ||
| English alias | (-)-Mandelic acid | mandelic_acid | s9003 | 1mcz | D-(-)-Mandelic acid, puriss., >=99.0% (T) | NCGC00166022-01 | (-)-(R)-Mandelate | D70151 | (-)-(R) alpha-hydroxybenzeneacetic acid | DTXSID4046523 | SR-01000946767-1 | (-)-alpha-Hydroxyphenylacetic acid | | ||
| CAS number | 611-71-2 | molecular formula | C8H8O3 |
| molecular weight | 152.15 g/mol | Exact mass | 10mM in DMSO |
| PSA | 57.500 Ų | logp | 0.6 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS05
Signal word:
Danger
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害 H318: 造成严重的眼睛损伤
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
WGK Germany:
1
Personal protective equipment:
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
611-71-2 | (R)-(−)-Mandelic acid.pdf





