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sodium oxamate

CAS number:565-73-1    molecular formula:C2H2NNaO3

overview

compound introduction

草酸钠是糖异生和糖酵解的抑制剂。由于癌细胞通常依赖糖酵解来产生 ATP,因此草酸钠具有作为抗癌化合物的意义 Sodium oxamate is an inhibitor of gluconeogenesis and glycolysis. As cancer cells are often dependent on glycolysis for ATP production, sodium oxamate has implications as an anticancer compound. An inhibitor of gluconeogenesis useful for anticancer research Application Sodium oxamate, an inhibitor of LDH-C4, prevented the AR induced by lysophosphatidylcholine (LPC) or NADH. Oxamic acid sodium salt is an lactic acid dehydrogenase. Sperm suspension and cytosol fraction activities were inhibited by sodium oxamate. As cancer cells are often dependent on glycolysis for ATP production, sodium oxamate has implications as an anticancer compound.

Specs

Chinese alias草氨酸钠盐 | 草酸单酰胺钠盐 | 氨基氧乙酸 钠盐
English aliasOxamic acid, sodium salt | EINECS 209-290-5 | O 2751 | HY-W013032A | FT-0632400 | MFCD00044553 | NCGC00261598-01 | Oxamic acid sodium salt | Acetic acid, aminooxo-, monosodium salt | AKOS024462579 | EU-0100913 | DTXSID1060342 | Oxamic acid (sodium) | A853
CAS number565-73-1molecular formulaC2H2NNaO3
molecular weight111.03Exact mass≥98%
PSA83.2logp-

numbering system

CAS565-73-1
WikidataQ72508045
ChEMBL IDCHEMBL1256289
PubChem CID5242
Nikkaji NumberJ188.429H
DSSTox Substance IDDTXSID1060342
European Community (EC) Number209-290-5
PubChem Reference Collection SID505547854

physicochemical properties

复杂性90.9
Exact Mass110.99323721
形式电荷0
重原子计数7
Molecular Weight111.03
Monoisotopic Mass110.99323721
可旋转键计数1
氢键供体计数1
氢键受体计数3
共价键单元计数2
同位素原子计数0
拓扑极性表面积83.2 Ų
定义键立体中心计数0
定义原子立体中心计数0
未定义键立体中心计数0
未定义原子手性中心计数0

Safety information

No safety information yet

Production methods and uses

purpose
工业应用参考:
工业分类参考:仪器仪表制造业。 应用场景参考:在环境监测、水资源分析、矿产检测、农残筛查和大气污染研究等方向具备潜在应用空间 。 作用参考:可作为基础工业材料参与合成、提纯或改性过程,为后续产品制造和工艺放大提供支撑 。 选型提示:实际选型应结合产品定位、纯度要求、设备精细化程度和现场环境综合判断,不宜仅凭单一指标决定 。

Related

upstream information

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downstream information

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MSDS

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