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Phorbol 12-myristate 13-acetate(PMA)

Dangerous Goods

CAS number：16561-29-8    molecular formula：C36H56O8

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numbering system
physicochemical properties
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overview

compound introduction

佛波醇12-十四酸酯13-乙酸酯 (PMA) 是一种佛波酯，是蛋白激酶 C (PKC) 和 SphK 的激活剂。Phorbol 12-myristate 13-acetate 是 NF-κB 激活剂。Phorbol 12-myristate 13-acetate 可诱导 THP-1 细胞分化； Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator. Phorbol 12-myristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells

Specs

Chinese alias-
English aliasPhorbol 13 Acetate 12 Myristate | (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate | Bio1_001278 | Bio2_0003
CAS number16561-29-8molecular formulaC36H56O8
molecular weight616.83 g/molExact mass-
PSA130.000 Ųlogp6.500

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P264: 处理后要彻底洗手。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US)， Eyeshields， Gloves
RTECS：
QH4377000
UN Number：
2811
Packing Group：
Ⅰ

Production methods and uses

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