compound introduction
含1.5分子结晶水者为棕红色结晶或粉末。不含结晶水是为绿黄色。约在180℃时失去结晶水，在180℃以上变黑，到300℃时也不熔化。溶于醇、丙酮及稀碱溶液，微溶于乙醚，几乎不溶于水，苯和氯仿。在强酸介质中呈现黄色，在微酸性中呈玫瑰红色，中性介质中呈淡紫色，在强碱性介质中呈紫色再为黄色。 Gallein is a cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ~400 nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities. Gallein is reported to exhibit prophylactic efficacy against carrageenan-induced neutrophil recruitment and tissue swelling in a murine paw edema model. Gallein is an inhibitor of G β and G γ An inhibitor of Gβγ-dependent cellular activities which binds to Gβγ with high affinity
