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5,5-Diphenylhydantoin sodium salt

Dangerous Goods

CAS number:630-93-3    molecular formula:C15H11N2O2Na

overview

compound introduction

无臭,味苦;微有吸湿性;在空气中渐渐吸收二氧化碳,分解成苯妥英;水溶液呈碱性反应,常因部分水解而发生浑浊;溶于水和乙醇,不溶于氯仿或乙醚。 Product Describtion: 5,5-Diphenylhydantoin sodium salt is a derivative of phenytoin. 5,5-Diphenylhydantoin is used for treating epilepsy and has antiepileptic activity. It functions by blocking the sodium channels and modulates excitation of neurons. However, the side effects include hypertrichosis and overgrowth of gum tissue around the teeth. It promotes proliferation of the neural stem cells by modulating growth factors. Diphenylhydantoin is toxic and induces apoptosis in cultured cerebellar granule neurons. Product Application: 5,5-Diphenylhydantoin sodium salt has been used in the cream preparation for treating burn wounds,in seizure behavior testing as an anticonvulsant in Drosophila,in in vivo embryo toxicity test in mouse embryonic stem cells.

Specs

Chinese alias5,5-二苯基-2,4-咪唑烷二酮钠盐 | 5,5-二苯基海因 钠盐 | 苯妥英 | 5,5-联苯基乙内酰脲 | 5,5-二苯乙内酰脲钠 | 5,5-二苯基乙内酰脲钠盐
English aliasMLS000554076 | Phenytoin sodium (USP:JAN) | 5,5-Diphenylhydantoin sodium | Dilantin Infatabs | Dilantin Suspension | Epanutin | sodium;5,5-diphenylimidazolidin-3-ide-2,4-dione | 5,5-diphenylhydantoin sodium sigmaultra | Aladdin | Dihydan | Phenytoin sodiu
CAS number630-93-3molecular formulaC15H11N2O2Na
molecular weight274.25 g/molExact mass≥98%
PSA47.200 Ųlogp-

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram:
GHS06 , GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒 H351: 怀疑引起遗传缺陷 H302: 吞食有害 H317: 可能引起皮肤过敏反应 H372: 通过长时间或反复暴露对器官造成损害 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P272: 被污染的工作服不允许离开工作场所 P333+P313: 如发生皮肤刺激或皮疹:求医/
WGK Germany:
3
Personal protective equipment:
Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges
RTECS:
MU1400000

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

Found 1 shareMSDS
630-93-3 | Phenytoin sodium.pdf