5'-脱氧腺苷是腺苷的类似物。在S-腺苷甲硫氨酸（SAM）的降解反应中，5'-脱氧腺苷是中间体。5'-脱氧腺苷用于研究磷酸甲基嘧啶合酶，谷氨酸突变酶和5'-甲基硫代腺苷磷酸化酶的运动学。另外，将5'-脱氧腺苷用作质谱标准和胸苷磷酸化酶活性筛选抑制剂。最后，如果进行5'-脱氧腺苷脱氨酶（DadD）分析，则5'-脱氧腺苷起底物的作用。 5'-Deoxyadenosine 是正常受试者尿液中发现的氧化核苷。5'-Deoxyadenosine 具有抗正痘活性。 应用 5′-脱氧腺苷已用于： 作为质谱中的标准品 作为筛选胸苷磷酸化酶活性的抑制剂 作为 5′-脱氧腺苷脱氨酶（DadD）试验的底物 5′-Deoxyadenosine is an analog of adenosin. In the degradation reaction of S-adenosylmethionine (SAM), 5′-Deoxyadenosine is an intermediate. 5′-Deoxyadenosine is used to study the enzyme kinematics of phosphomethylpyrimidine synthase, glutamate mutase, and 5′-methylthioadenosine phosphorylase. In addition, 5′-Deoxyadenosine has been used as a mass spectroscopy standard, and a thymidine phosphorylase activity screening inhibitor. Finally, 5′-Deoxyadenosine functions as a substrate if 5′-Deoxyadenosine deaminase (DadD) assay.
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5′-Deoxyadenosine
Dangerous GoodsCAS number：4754-39-6 molecular formula：C10H13N5O3
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Specs
| Chinese alias | 5-脱氧腺嘌呤核苷 | ||
| English alias | 5′-dAdo | ||
| CAS number | 4754-39-6 | molecular formula | C10H13N5O3 |
| molecular weight | 251.24 g/mol | Exact mass | ≥98% |
| PSA | 119.000 Ų | logp | -0.600 |
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WGK Germany：
3
RTECS：
AU7358650
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