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8-Chloro-cAMP

Dangerous Goods

CAS number：41941-56-4    molecular formula：C10H11ClN5O6P

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overview

compound introduction

8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity. In Vitro 8-Chloro-cAMP markedly inhibits vascular smooth muscle cell (VSMC) proliferation in vitro, reduces protein kinase A (PKA) RIα subunit expression, and induces PKA RIIβ subunit expression. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo In rat bearing balloon injury, 8-Chloro-cAMP (12 mg/kg) reduces, in a dose-dependent manner, neointimal area and neointima/media ratio after balloon injury. 8-Chloro-cAMP shows a reduction of proliferative activity of VSMCs in vivo . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Specs

Chinese alias8-氯环腺苷酸
English alias(4AR,6R,7R,7AS)-6-(6-AMINO-8-CHLORO-PURIN-9-YL)-2-OXO-TETRAHYDRO-2LAMBDA*5*-FURO(3,2-D)(1,3,2)DIOXAPHOSPHININE-2,7-DIOL | 8-Chloroadenosine 3',5'-monophosphate | DB13046 | Tocladesine | 8-Chloroadenosine 3',5'-cyclic-monophosphate | 8-CHLORO-CYCLIC ADENOS
CAS number41941-56-4molecular formulaC10H11ClN5O6P
molecular weight363.65 g/molExact mass≥99%
PSA155.000 Ųlogp-1.600

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WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter

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