Alkaline hydrolysis of mevalonolactone gives mevalonate. Mevalonate is a precursor of farnesyl and geranylgeranyl pyrophosphates. These pyrophosphates are required for protein prenylation. 用途 (±)-Mevalonolactone is used to: • study the effect of statin on the prenylation of Ras and Rho GTPases • analyse the isoprenoid biosynthesis pathways in Listeria monocytogenes • study the the effects of statins on proliferation and migration of HUVECs (HGF-induced human umbilical vein endothelial cells) Product Introduction Alkaline hydrolysis of mevalonolactone gives mevalonate. Mevalonate is a precursor of farnesyl and geranylgeranyl pyrophosphates. These pyrophosphates are required for protein prenylation. Application (±)-Mevalonolactone is used to: • study the effect of statin on the prenylation of Ras and Rho GTPases • analyse the isoprenoid biosynthesis pathways in Listeria monocytogenes • study the the effects of statins on proliferation and migration of HUVECs (HGF-induced human umbilical vein endothelial cells)
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DL-Mevalonolactone
CAS number：674-26-0 molecular formula：C6H10O3
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| Chinese alias | 甲瓦龙酸内酯 | 3,5-二羟基-3-甲基戊酸内酯 | DL-甲羟戊酸内醋 | (±)-3-羟基-3-甲基 δ-戊内酯, (±)-β-羟基-β-甲基-δ-戊内酯 | ||
| English alias | LMFA07040003 | 1RJ06DC41B | MEVALONOLACTONE, DL- | Mevalonic acid .delta.-lactone | 009D7F12-69C6-4BBF-A66D-12BA84648C72 | AS-65830 | HMS2097E22 | NCGC00179453-01 | .beta.-Hydroxy-.beta.-methyl-.delta.-valerolactone | 2H-PYRAN-2-ONE, TETRAHYDRO-4-HYDROXY- | ||
| CAS number | 674-26-0 | molecular formula | C6H10O3 |
| molecular weight | 130.14 g/mol | Exact mass | 10mM in DMSO |
| PSA | 46.500 Ų | logp | -0.300 |
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